Document Type
Review
Subject Areas
Chemistry; Pharmaceutical Organic Chemistry
Keywords
Aromatics, Heterocyclic Compounds, Anti-inflammatory, Anticancer. NSAIDs, COX-2 inhibitor, LOX-inhibitor, Toll-inhibitor, Antioxidant.
Abstract
As the second leading cause of mortality worldwide, cancer poses a severe threat to human health. Chronic inflammation has recently been linked to an increased risk for a number of malignancies, suggesting that reducing inflammation could be a useful approach to both cancer prevention and treatment. This review delves into the connection between inflammation and cancer and outlines the current use of anti-inflammatory drugs as potentially effective cancer prevention and therapy strategies. we herein describe the main relation and the mechanisms underlying the anti-cancer outcomes of anti-inflammatory agents; namely Non-Steroidal Anti-inflammatory Drugs (NSAIDs), COX-2 inhibitors, LOX-inhibitors, Toll- inhibitors, and antioxidant agents.
How to Cite This Article
Fatahala, Samar Said; El-Hameed, Rania Helmy Abd; Mohamed, Mosaad Sayed; and El-tawab, Neama Abdallah Abd
(2024)
"Dual Activity of Aromatic and Heterocyclic Compounds as Anti-inflammatory and Anticancer promising agents,"
Trends in advanced sciences and technology: Vol. 1, Article 21.
DOI: https://doi.org/10.62537/2974-444X.1022
Available at:
https://tast.researchcommons.org/journal/vol1/iss1/21
